A 1-1 draw against Leicester on Saturday left Tottenham manager Pochettino counting the cost of five games without a victory.
West Bromwich Albion, Bournemouth and Bayer Leverkusen also held Tottenham to draws, while Liverpool knocked them out of the League Cup.
Those setbacks have punctured the buoyant mood at White Hart Lane since their impressive win against Manchester City.
But Pochettino knows injuries have been at the root of Tottenham's problems and he hopes the results will pick up once the wounded return to action.
Harry Kane and Toby Alderweireld are still recovering from ankle and leg injuries respectively, while Moussa Sissoko is out suspended and Erik Lamela has been ill.
Kane and Alderweireld could return either against Leverkusen in the Champions League at Wembley on Wednesday or in the north London derby at Arsenal at the weekend.
Asked if he had endured a spell in management as frustrating as this, Pochettino said: "I don't remember having one.
"It is hard because the players come, maybe not injured, but with many problems and maybe play two games and with the small problems we have with Toby Alderweireld, Harry Kane, Sissoko's suspension and Erik Lamela on Saturday.
"Yes it is true it is a tough period when you play, play, play that you need all the squad available, but you need to adapt to the competition and we are happy.
"It is true we are disappointed with the last few results but in the same way we need to take positives in and keep working."
