The 49-year-old actress is "very flattered" to have picked up People magazine's annual accolade for the fifth time, and joked she'll be bragging to her good friend George Clooney, a double winner of the publication's 'Sexiest Man Alive' title.
She said: "I am very flattered. I'm going to mention that in my Christmas card to the Clooneys this year."
Despite her beauty, the Eat Pray Love star claims she felt "awkward" in her early years
She said: "People say, 'Oh, when Pretty Woman came out it must have really changed your life,' and it's kind of become this joke, but the truth is I was out of town when Pretty Woman came out.
"I was in another movie in this tiny little town that was showing Star Wars in its first run. I remember reading ... ''Pretty Woman came out this weekend and made this much money" and I thought, 'Is that a lot of money? Is that good? Is that great?' I didn't really know."
These days, the actress couldn't be happier with her personal life
She gushed: "I mean every day my husband walks in the door it's like a recurring dream. I'm like, 'Ah, he's back!' "
Source: All4Women